Searchable abstracts of presentations at key conferences in endocrinology

ea0025p291 | Steroids | SFEBES2011

Urinary tetrahydrodeoxycorticosterone excretion is a significant independent predictor of LV mass in patients with chronic kidney disease

McQuarrie Emily , Mark Patrick , Patel Rajan , Fraser Robert , Davies Eleanor , Steedman Tracey , Connell John , Freel E Marie

Aim: Increasing left ventricular mass index (LVMI) is associated with a poor prognosis in patients with chronic kidney disease (CKD). Blockade of the mineralocorticoid receptor (MR) in CKD leads to improvement in proteinuria and LV mass. However, the MR can be activated by aldosterone, cortisol and deoxycorticosterone (DOC) and their relative contribution to adverse events in CKD is unclear. We aimed to assess the correlation between mineralocorticoid excretion and LVMI in pat...